Premium
Nucleotides. Part XLI . The 2‐dansylethoxycarbonyl ( 2‐{[5‐(dimethylamino)naphthalen‐1‐yl]sulfonyl}ethoxycarbonyl; dnseoc) group for protection of the 5′‐hydroxy function in oligodeoxyribonucleotide synthesis
Author(s) -
Bergmann Frank,
Pfleiderer Wolfgang
Publication year - 1994
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19940770123
Subject(s) - chemistry , sulfonyl , phosphoramidite , protecting group , stereochemistry , nucleotide , group (periodic table) , combinatorial chemistry , organic chemistry , oligonucleotide , biochemistry , dna , alkyl , gene
Use of the 2‐dansylethoxycarbonyl ( 2‐{[5‐(dimethylamino)naphthalen‐1‐yl]sulfonyl}ethoxycarbonyl; Dnseoc) group as an intermediate 5′‐OH protecting group in oligodeoxyribonucleotide synthesis using the automated phosphoramidite approach is described in a model study to an alternative strategy in RNA synthesis.