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Asymmetric Catalysis by Vitamin B 12 : The Isomerization of Achiral Aziridines to Optically Active Allylic Amines
Author(s) -
Zhang Zhong Da,
Scheffold Rolf
Publication year - 1993
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19930760719
Subject(s) - chemistry , isomerization , optically active , allylic rearrangement , catalysis , organic chemistry , medicinal chemistry , stereochemistry
Achiral N ‐acylaziridines are isomerized to optically active N ‐acyl‐allylamines in ee's of up to 95% by catalytic amounts of cob(I)alamin in MeOH.
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