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2‐(Tributylstannyl)‐1‐{[2‐(trimethylsilyl)ethoxy]methyl}‐1 H ‐indole: Synthesis and use as a 1 H ‐indol‐2‐yl‐anion equivalent
Author(s) -
Palmisano Giovanni,
Santagostino Marco
Publication year - 1993
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19930760622
Subject(s) - chemistry , indole test , trimethylsilyl , alkoxy group , ion , medicinal chemistry , stereochemistry , organic chemistry , alkyl
Pd‐Catalyzed reaction of 2‐(tributylstannyl)‐1‐{[2‐(trimethylsilyl)ethoxy]methyl}‐1 H ‐indole ( 5 ) with a variety of aryl, heteroaryl, vinyl, and allyl halides provides an efficient entry to the corresponding cross‐coupled products (see Table ).