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On the Novel Free Porphyrins Corallistin B, C, D, and E: Isolation from the demosponge Corallistes sp. of the Coral Sea and Reactivity of Their Nickel 55 (II) Complexes toward Formylating Reagents
Author(s) -
D'Ambrosio Michele,
Guerriero Antonio,
Pietra Francesco,
Debitus Cécile,
Ribes Olivier
Publication year - 1993
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19930760410
Subject(s) - chemistry , sponge , reactivity (psychology) , formylation , stereochemistry , coral , porphyrin , nickel , organic chemistry , catalysis , ecology , botany , medicine , alternative medicine , pathology , biology
Reported here are the novel free porphyrins corallistin B, C, D, and E, isolated as methyl esters 2a , 3a , 4a , and 5a , respectively, from the sponge Corallistes sp. (Lithistida) collected at the basis of the south New Caledonian coral reef. A protocol is also established for formylation of their Ni II complexes, which show a different reactivity pattern toward DMF/POCl3 from metal complexes of deuteroporphyrins. Together with corallistin A, Previously isolated as the methyl ester 1a , and the known deuteroporphyrin IX (isolated as 6a ) also present in the sponge, the new corallistins, which may be thought to derive from protoporphyrin via heme, account for an amazing 60% of the EtOh extract from the sponge.