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Enantiomeric Purities of ( R )‐ and ( S )‐Camphors from the Chiral Pool and High Enantiomeric Purities in General
Author(s) -
Rautenstrauch Valentin,
Lindström Mikael,
Bourdin Bernadette,
Curie Jane,
Oliveros Esther
Publication year - 1993
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19930760140
Subject(s) - chemistry , enantiomer , enantiomeric excess , chiral stationary phase , organic chemistry , chiral derivatizing agent , chromatography , enantioselective synthesis , chiral column chromatography , catalysis
The commercially available camphor enantiomers are extensively used in several important areas of chemical research, and it seems that they are often considered to be enantiomerically pure (the meaning of the term is discussed); there are certainly no enantiomeric purities (e.p.) on record. By standard GLC on a modified cyclodextrin column, we have now found five commercial ( R )‐camphors to have the same high but imperfect e.p., (99.62 ± 0.02)% ( R ), a sixth a slightly higher e.p., (99.76 ± 0.06) % ( R ), and three ( S )‐camphors to have different and lower e.p. Nailing down these e.p. is useful by itself and puts into focus the sensitivity of present day GLC, and how little is know about high e.p. in general.