Pterin Chemistry. Part 92. . Loading experiments with 6α,β‐tetrahydro‐ L ‐[3′‐ 2 H 1 ] biopterin | Zendy

Adler Carmen | Zendy; Curtius HansChristoph | Zendy; Wetzel Erich | Zendy; Viscontini Max | Zendy; Giudici Tullio A. | Zendy; Blaskovics Milan | Zendy; Rolland Marie O. | Zendy; Guibaud Pierre | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Pterin Chemistry. Part 92. . Loading experiments with 6α,β‐tetrahydro‐ L ‐[3′‐ 2 H 1 ] biopterin

Author(s) -

Adler Carmen,

Curtius HansChristoph,

Wetzel Erich,

Viscontini Max,

Giudici Tullio A.,

Blaskovics Milan,

Rolland Marie O.,

Guibaud Pierre

Publication year - 1992

Publication title -

helvetica chimica acta

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.74

H-Index - 82

eISSN - 1522-2675

pISSN - 0018-019X

DOI - 10.1002/hlca.19920750423

Subject(s) - biopterin , pterin , chemistry , intramolecular force , urine , stereochemistry , isotopomers , biochemistry , organic chemistry , cofactor , molecule , enzyme , tetrahydrobiopterin

6α,β‐Tetrahydro‐ L ‐[3′‐ 2 H 1 ]biopterin ([3′‐ 2 H 1 ]‐ 1 ) was administered orally to two primapterinuric patients in order to investigate the biosynthetic pathway of 7‐substituted pterins in humans. L ‐Primapterin ( 2 ) and L ‐biopterin were isolated from urine after loading and measured by GC/MS. L ‐Biopterin and L ‐primapterin were labelled with 2 H to an equal extent. From this result, one can conclude that L ‐primapterin is formed from tetrahydro‐ L ‐biopterin, very probably via an intramolecular rearrangement.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research