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Channel‐Type Molecular Structures. Part 2 . Synthesis of Bouquet‐Shaped Molecules Based on a β‐Cyclodextrin Core
Author(s) -
Canceill Josette,
Jullien Ludovic,
Lacombe Liliane,
Lehn JeanMarie
Publication year - 1992
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19920750315
Subject(s) - chemistry , cyclodextrin , amphiphile , molecule , bilayer , side chain , membrane , stereochemistry , lipid bilayer , derivative (finance) , core (optical fiber) , combinatorial chemistry , organic chemistry , copolymer , biochemistry , polymer , materials science , economics , financial economics , composite material
A new series of channel‐type molecules presenting the features of potential transmembrane structures is described. They result from the grafting of amphiphilic side chains on a β‐cyclodextrin derivative 3 that constitutes the organizing core. They belong to the ‘bouquet’ family ( B ). Compounds bearing poly(oxyethylene) side chains, B CD o16 and 17 , and their polymethylene analogues B CD C18 and 19 , were synthesized. The properties investigated emphasize the suitability of such molecules to be incorporated into lipid bilayer membranes.