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Reduction of Aldehydes and Ketones by Transition Metal Hydrides. Part 2. Reaction of trans , trans ‐[WH(CO) 2 (NO)(PMe 3 ) 2 ] with pyridine, functionalized aldehydes, and ketones
Author(s) -
Van Der Zeijden Adolphus A. H.,
Berke Heinz
Publication year - 1992
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19920750211
Subject(s) - chemistry , denticity , ketone , medicinal chemistry , pyridine , ligand (biochemistry) , transition metal , tungsten , stereochemistry , metal , catalysis , organic chemistry , biochemistry , receptor
The reaction of trans , trans ‐[WH(CO) 2 (NO)(PMe 3 ) 2 ] ( 1 ) with (pyridin‐2‐yl)‐substituted aldehydes and ketones, (pyridin‐2‐yl)C(O)R where R = H, Me, Ph, pyridin‐2‐yl, and with 6‐methylpyridine‐2‐carbaldehyde was studied. In all cases, facile insertion of the CO bond into the WH bond was observed, with rapid subsequent extrusionof a coordinated CO ligand affording O , N ‐bidentate coordinated tungsten alkoxides. Only in case of pyridine‐2‐carbaldehyde and di(pyridin‐2‐yl) ketone, the initial n 1 O‐bonded insertion product could be observed as unstable intemediates by low‐temperature NMR.