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Synthese von Makrocyclen durch Ringerweiterung von 14gliedrigen cyclischen Imiden
Author(s) -
Koch Thomas,
Ognyanov Vassil I.,
Hesse Manfred
Publication year - 1992
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19920750104
Subject(s) - chemistry , ring (chemistry) , cleavage (geology) , stereochemistry , derivative (finance) , organic chemistry , geotechnical engineering , fracture (geology) , financial economics , engineering , economics
Synthesis of Macrocyles by Ring Enlargement of 14‐Membered Cyclic Imides In the presence of a base, cyclododecanone derivative 2 , activated in α‐position by an allyloxycarbonyl group, underwent ring enlargement with isocyanates to give 14‐membered imides ( Schemes 1–3 ). Cleavage of the activating group gave new 14‐membered imides which could be transformed by further ring‐enlargement reactions into new macrocyclic compounds.