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New Dolabellane Derivatives from the Brown Alga Dictyota pardalis
Author(s) -
Wright Anthony D.,
König Gabriele M.,
Sticher Otto,
Lubini Paolo,
Hofmann Patrick,
Dobler Max
Publication year - 1991
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19910740822
Subject(s) - chemistry , stereochemistry , botany , biology
Reinvestigation of the brown alga Dictyota pardalis f. pseudohamata C RIBB led to the crystallization of 1 and to the isolation of the two new dolabellane derivatives 2 and 3 . X‐Ray analysis of 1 and 2 , together with detailed 1D‐and 2D‐NMR studies on 2 and 3 , allowed their structures to be elucidated as (1 R *,3 S *,7 S *,11 R *,4 Z )‐dolabella‐4,8(17), 12(18)‐triene‐3,7‐diol ( 1 ), (1 R *,3 S *,4 S *,7 S *,8 S *,11 R *,14 R *,12 E )‐3,4:7,8‐diepoxydolabe11‐12‐ene‐14, 18‐diol ( 2 ), and (1 R *,3 S *,4 S *,7 S *,8 S *,11 R *,14 R *)‐3,4:7,8‐diepoxy‐l,4,8,12,12‐pentamethylbicyclo[9. 3. 0]tetra‐decan‐14‐ol( 3 ).