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Enantioselective Optode Membranes with Enantiomer Selectivity for ( R )‐ and ( S )‐l‐Phenylethylammonium Ions
Author(s) -
Holý Petr,
Morf Werner E.,
Seller Kurt,
Simon Wilhelm,
Vigneron JeanPierre
Publication year - 1990
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19900730505
Subject(s) - optode , chemistry , membrane , enantiomer , selectivity , ionophore , enantiomeric excess , ammonium , ion , enantioselective synthesis , combinatorial chemistry , inorganic chemistry , organic chemistry , biochemistry , catalysis
The recently developed general principle of ion‐selective optode membranes, based on conventional ionophores, was employed to design a new approach to the determination of enantiomeric excess. Highly lipophilic chiral crown derivatives, exhibiting a high selectivity for a chiral ammonium guest cation, are combined with a H + ‐selective chromoionophore in a plasticized PVC membrane. The enantiomer recognition process is translated by this sensor with an optical transduction into a signal easily measured by a conventional spectrophotometer, and enantiomeric excess can be determined without the need for polarized light. Characteristics and a theoretical description of these new optode membranes are given.