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Corallistin A, a second example of a free porphyrin from a living organism. Isolation from the demosponge Corallistes sp. of the coral see and inhibition of abnormal cells
Author(s) -
D'Ambrosio Michele,
Guerriero Antonio,
Debitus Cécile,
Ribes Olivier,
Richer De Forges Bertrand,
Pietra Francesco
Publication year - 1989
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19890720704
Subject(s) - chemistry , coral , porphyrin , sponge , organism , isolation (microbiology) , stereochemistry , zoology , ecology , biochemistry , microbiology and biotechnology , botany , paleontology , biology
Abstract It is shown that the demosponge Corallistes sp. (Tetractinomorpha, Lithistida, Corallistidae) collected in the Coral Sea, contains corallistin A ( 1 ), the second example, of a free porphyrin from a living organism. The compound proved to be active against the Kb cell line. In contrast with the geoporphyrins which do not bear any O‐atom corallistin A ( 1 ) carries two carboxylic groups.