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Structure‐Activity Relationship in Ambergris‐Type Woody Odorants possessing a hydronaphthalene skeleton
Author(s) -
Vial Christian,
Thommen Walter,
Näf Ferdinand
Publication year - 1989
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19890720628
Subject(s) - chemistry , skeleton (computer programming) , organic chemistry , stereochemistry , medicinal chemistry , computer science , programming language
A series of methyl hydronaphthyl alcohols, formates, acetates, and ketones were prepared and their odour properties evaluated. Minor structural changes, even opposite to the osmophoric group, were found to have major effects on the odour. 13 CNMR shift assignments of the hydronaphthyl derivatives are presented.