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Synthese von ( R )‐β, β‐Carotin‐2‐ol und (2 R , 2′ R )‐β, β‐Carotin‐2,2′‐diol
Author(s) -
Gut Samuel,
Wolleb Heinz,
Pfander Hanspeter
Publication year - 1989
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19890720312
Subject(s) - chemistry , geraniol , epoxide , diol , stereochemistry , enantiomer , optically active , organic chemistry , catalysis , chromatography , essential oil
Synthesis of ( R )‐β, β‐Caroten‐2‐ol and (2 R , 2′ R )‐β, β‐Carotene‐2,2′‐diol Starting from geraniol, the two carotenoids ( R )‐β, β‐caroten‐2‐ol ( 1 ) and (2 R , 2′ R )‐β, β‐carotene‐2,2′‐diol ( 3 ) were synthesized. The optically active cyclic building block was obtained by an acid‐catalysed cyclisation of the epoxide ( R )‐ 4 . The enantiomeric excess of the product was > 95 %.