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Assignment of Quaternary Carbon Atoms in 13 C‐NMR Spectroscopy: Application of an improved heteronuclear 2D‐NOE experiment
Author(s) -
Bigler Peter
Publication year - 1988
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19880710217
Subject(s) - heteronuclear molecule , chemistry , quaternary carbon , nuclear overhauser effect , quaternary , dipole , nuclear magnetic resonance spectroscopy , molecule , two dimensional nuclear magnetic resonance spectroscopy , spectroscopy , scalar (mathematics) , nuclear magnetic resonance , computational chemistry , analytical chemistry (journal) , stereochemistry , organic chemistry , physics , enantioselective synthesis , paleontology , geometry , mathematics , quantum mechanics , biology , catalysis
Nuclear Overhauser effects (NOE) between protons and heteronuclei can be of great value for the assignment of quaternary nuclei, and they can be very informative and unique in view of stereochemistry and molecular dynamics. The application of a modified 2D‐NMR experiment for the assingment of quaternary carbon atoms of a medium‐sized molecule is demonstrated. Compared to NMR experiments designed to detect scalar instead of dipolar interactions, measuring times are considerably longer, but data analysis is in many cases more straightforward.