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Synthese von Dimethyl‐4a,8a‐methanophthalazin‐1,4‐dicarboxylat und Derivaten
Author(s) -
Neidlein Richard,
Tadesse Lema
Publication year - 1988
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19880710127
Subject(s) - chemistry , tetrazine , nucleophile , dimethyl fumarate , bicyclic molecule , medicinal chemistry , organic chemistry , catalysis , psychology , psychiatry , multiple sclerosis
Synthesis of Dimethyl 4a,8a‐Methanophthalazine‐1,4‐dicarboxylate and Derivatives Diels ‐ Alder reaction with inversed electron demand of 1 H ‐cyclopropabenzol 1 with dimethyl 1,2,4,5‐tetrazine‐3,6‐dicarboxylate ( 2 ) yields dimethyl‐4a,8a‐methanophthalazine‐1,4‐dicarboxylate ( 3 ). The reactions of 3 with nucleophiles are also described.
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