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Isolierung und Strukturaufklärung von 36 Diterpenoiden aus Trichomen von Plectranthus edulis (V ATKE ) T.T. A YE
Author(s) -
Künzle Josef Max,
Rüedi Peter,
Eugster Conrad Hans
Publication year - 1987
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19870700726
Subject(s) - chemistry , plectranthus , stereochemistry , abietane , terpenoid , botany , biology , lamiaceae
Isolation and Structure Elucidation of 36 Diterpenoids from Leaf‐Glands of Plectranthus edulis (V ATKE ) T.T. A YE Analysis of the polar diterpenoids from the yellow glands of the title plant from Kenya and Abyssinia led to the identification of several novel abietanoids. Main compound is the known edulon A ( 40 ), a 5(4→3) abeo ‐abietane. Minor compounds include 6 different royleanones, 15 spirocoleons, 3 vinylogous quinones, 8 acylhydroquinones (as their 6,7‐dioxo compounds or the tautomeric disophenols), 2 naphthaquinones (as the 1,10‐ seco ‐abietanoids), and deacetyledulon A. The known coleon‐A‐lactone (37) now has also been found in Plectranthus edulis. The intermediacy of the γ‐enollactol 44 , combined with a leaving group on C(3) is postulted to explain the biogenesis of the unusual 4 H ‐5‐oxaaceanthrylen skeleton of edulon A.