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A Simple and Effective Chemical Phosphorylation Procedure for Biomolecules
Author(s) -
Bannwarth Willi,
Trzeciak Arnold
Publication year - 1987
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19870700122
Subject(s) - chemistry , phosphorylation , serine , biomolecule , threonine , protein phosphorylation , oligonucleotide , tyrosine , tyrosine phosphorylation , peptide , biochemistry , combinatorial chemistry , protein kinase a , dna
A general chemical phosphorylation method based on P(III) chemistry has been developed. The system is demonstrated for the phosphorylation of oligonucleotides, directly after their synthesis on a solid support, and for the O ‐phosphorylation of serine, threonine, and tyrosine as well as for a serine‐containing peptide.
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