Premium
Further Saponins from Phytolacca dodecandra L′H ERIT
Author(s) -
Dorsaz AnneChristine,
Hostettmann Kurt
Publication year - 1986
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19860690827
Subject(s) - chemistry , hydrolysis , oleanolic acid , saponin , cleavage (geology) , stereochemistry , two dimensional nuclear magnetic resonance spectroscopy , acid hydrolysis , organic chemistry , medicine , alternative medicine , geotechnical engineering , pathology , fracture (geology) , engineering
Three new bidesmosidic saponins 1 – 3 have been isolated from the berries of Phytolacca dodecandra L′H ERIT ( Phytolaccaeae ). The structures have been established by spectroscopic ( 1 H‐NMR, 13 C‐NMR, FAB‐MS, DCI‐MS, and GC/MS) and chemical methods (acid, basic, and enzymatic hydrolysis). Saponins 1 and 3 are tetra‐ and pentaglycosides of oleanolic acid, whereas 2 is a tetraglycoside of bayogenin. The corresponding prosapogenins 1a ‐ 3a , obtained by cleavage of a glucose unit esterified at C(28), exhibited strong molluscicidal activity against schistosomiasis‐transmitting snails.