Premium
Synthèse d'une nouvelle depsidone dérivée de l'acide furfurique, le diméthoxy‐3,8‐(diméthoxy‐2,4‐méthoxycarbonyl‐5‐diméthyl‐3,6‐benzyl)‐9‐triméthyl‐1,4,6‐oxo‐11‐11 H ‐dibenzo[ b , e ]dioxépinne[1,4]carboxylate‐7 de méthyle
Author(s) -
Gunzinger Jan,
Tabacchi Raffaele
Publication year - 1985
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19850680719
Subject(s) - chemistry , orcinol , stereochemistry , carboxylate , derivative (finance) , intramolecular force , medicinal chemistry , organic chemistry , financial economics , economics
Synthesis of a New Depsidone, Derivative of Furfuric Acid: Methyl 3,6‐dimethoxy‐9‐(2,4‐dimethoxy‐5‐methoxycarbonyl‐3,6‐dimethylbenzyl)‐1,4,6‐trimethyl‐11‐oxo‐11 H ‐dibenzo[ b , e ] [1,4]dioxepin‐7‐carboxylate The total synthesis of the title compound 1b is described. Starting from simple orcinol and β‐orcinol units, the benzophenone 4 has been prepared. Using a biomimetic reaction, the intramolecular oxydative coupling, lead to the grisadienedione 25 . By thermal interconversion and permethylation, the depsidone 1b has been obtained.