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Synthèse des ( R )‐ et ( S )‐ O ‐isopropylidène‐1,2‐glycérols. Détermination de la pureté optique
Author(s) -
Hirth Georges,
Walther Willy
Publication year - 1985
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19850680708
Subject(s) - chemistry , glycerol , derivatization , acetonide , chromatography , high performance liquid chromatography , organic chemistry , triamcinolone acetonide , ophthalmology , medicine
Synthesis of the ( R )‐ and ( S )‐Glycerol Acetonides. Determination of the Optical Purity The optical purity of ( R )‐glycerol acetonide ( 1 ) and ( S )‐glycerol acetonide ( 1 ′) has been determined with great accuracy by gas chromatography after derivatization. The optical purity of ( S )‐glycerol actonide prepared from D ‐mannitol was > 99.4% while for ( R )‐glycerol acetonide obtained from L ‐serine it was 95%.