Structure and Reactivity of Xanthocorrinoids. Part III . The first example of a pinacol‐type rearrangement in the corrin series | Zendy

Grüning Burghard | Zendy; Holze Gerhard | Zendy; Gossauer Albert | Zendy; Ernst Ludger | Zendy

Premium

Structure and Reactivity of Xanthocorrinoids. Part III . The first example of a pinacol‐type rearrangement in the corrin series

Author(s) -

Grüning Burghard,

Holze Gerhard,

Gossauer Albert,

Ernst Ludger

Publication year - 1985

Publication title -

helvetica chimica acta

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.74

H-Index - 82

eISSN - 1522-2675

pISSN - 0018-019X

DOI - 10.1002/hlca.19850680632

Subject(s) - chemistry , corrin , vicinal , stereochemistry , reactivity (psychology) , acetic acid , carbonyl group , medicinal chemistry , group (periodic table) , pinacol , ascorbic acid , organic chemistry , ring (chemistry) , catalysis , medicine , alternative medicine , food science , pathology

The transformation of the c ‐acetic‐acid chain of hexamethyl Co α, Co β‐dicyanocobyrinate into an ethyl group (→ 2 ) as well as the synthesis of the pentadecaalkyl‐cobalticorrin 6d from commercial cyanocobalamin are described. On reaction of 2 or 6d with O 2 in the presence of ascorbic acid, migration of the CH 3 group at C(5) to the vicinal position C(6) takes place concomitantly with the introduction of a carbonyl group at C(5).

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research