Skeletal Migrations Observed during the Cob(I)alamin‐Catalyzed Reduction of 4β‐( tert ‐Butyl)‐1β‐(1‐methylvinyl)cyclohexanecarbaldehyde | Zendy

Ziegler Carl B. | Zendy; Fischli Albert | Zendy

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Skeletal Migrations Observed during the Cob(I)alamin‐Catalyzed Reduction of 4β‐( tert ‐Butyl)‐1β‐(1‐methylvinyl)cyclohexanecarbaldehyde

Author(s) -

Ziegler Carl B.,

Fischli Albert

Publication year - 1985

Publication title -

helvetica chimica acta

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.74

H-Index - 82

eISSN - 1522-2675

pISSN - 0018-019X

DOI - 10.1002/hlca.19850680122

Subject(s) - chemistry , catalysis , reduction (mathematics) , cobalt , medicinal chemistry , scheme (mathematics) , stereochemistry , organic chemistry , geometry , mathematics , mathematical analysis

During the cob(I)alamin( 1(I) )‐catalyzed reduction of 3 , intermediate formation of 2 and final generation of 4–10 was observed (see Scheme 1, cf. Tables 1 and 2 ). Identical products in similar ratios were generated starting from either 2 or 3 . Accepting the intermediate formation of six interconnected cobalt complexes, i.e. A–F (cf. Scheme 2) , the generation of all the products observed can be explained.

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