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Synthese von neuen Morphin‐Teilstrukturen des Typs 15,16‐Secomorphinan
Author(s) -
Révész László
Publication year - 1984
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19840670627
Subject(s) - chemistry , morphine , stereochemistry , potency , opiate , receptor , pharmacology , biochemistry , in vitro , medicine
Synthesis of New Morphine Partial Structure 15,16‐Secomorphinan The synthesis of a new morphine partial structure, 15,16‐secomorphinan, is described. One of the series, (±)‐15, 16‐secocyclorphan (5) , has the analgesic potency of morphine and exhibits good binding to the opiate receptor.