Premium
On cardioactive steroids. XII. The synthesis of (natural) bufalin and α′‐isobufalin
Author(s) -
Wiesner Karel,
Tsai Thomas Y. R.,
Sen Alina,
Kumar Ravindra,
Tsubuki Masayoshi
Publication year - 1983
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19830660831
Subject(s) - bufalin , chemistry , yield (engineering) , simplicity , furan , simple (philosophy) , combinatorial chemistry , organic chemistry , biochemistry , thermodynamics , apoptosis , philosophy , epistemology , physics
An efficient and simple synthesis of bufalin (1) via furan‐containing intermediates is described. The same method was also used for the synthesis of α‐isobufalin (2) which was prepared with equal simplicity, but in lower yield.