Premium
New Sesquiterpenoids from Clary Sage Oil ( Salvia sclarea L.)
Author(s) -
Maurer Bruno,
Hauser Arnold
Publication year - 1983
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19830660734
Subject(s) - chemistry , sage , stereochemistry , nuclear physics , physics
Six sesquiterpenoids, ( R , 5 E )‐2, 12‐epoxycaryophyll‐5‐ene (1) , (2 R , 5 E )‐caryophyll‐5‐en‐12‐al (2) , (2 S , 5 E )‐caryophyll‐5‐en‐12‐al (3) , isospathulenol (4) , (1 R , 5 R )‐ 1,5‐epoxysalvial‐4(14)‐ene (5) , and salvial‐4(14)‐en‐l‐one (6) have been identified for the first time in clary sage oil ( Salvia sclarea L.). The structures and absolute configurations of 1–6 are corroborated by partial syntheses and their organoleptic properties are discussed. The compounds 5, 6 and mintsulfide (14) possess the rare C‐skeleton C , for which the semisystematic name ‘salvialane’ is proposed. The sesquiterpenoids 1–5 are new.