Ru‐Catalyzed Oxidations with Iodosylbenzene Derivatives. Substituent Effects on Selectivity in Oxidation of Sulfides and Alcohols | Zendy

Müller Paul | Zendy; Godoy José | Zendy

Premium

Ru‐Catalyzed Oxidations with Iodosylbenzene Derivatives. Substituent Effects on Selectivity in Oxidation of Sulfides and Alcohols

Author(s) -

Müller Paul,

Godoy José

Publication year - 1983

Publication title -

helvetica chimica acta

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.74

H-Index - 82

eISSN - 1522-2675

pISSN - 0018-019X

DOI - 10.1002/hlca.19830660618

Subject(s) - chemistry , substituent , selectivity , sulfoxide , catalysis , reactivity (psychology) , ring (chemistry) , alcohol oxidation , organic chemistry , carboxylic acid , medicinal chemistry , combinatorial chemistry , medicine , alternative medicine , pathology

Oxidation of sulfides with PhIO/RuCl 2 (PPh 3 ) 3 leads to sulfones. Electronwithdrawing substituents in the aromatic ring of PhIO reduce the reactivity and improves selectivity of the system. Thus, with m ‐iodosylbenzoic acid sulfides are converted to sulfoxide. Under the same conditions aliphatic primary alcohols are transformed to aldehydes with m ‐iodosylbenzoic acid, while PhIO affords carboxylic acids.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research