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Notiz zur Synthese von Alkyl‐, Cycloalkyl‐ und Aryl‐(4‐aminophenyl)‐sulfonen
Author(s) -
Courtin Alfred
Publication year - 1983
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19830660407
Subject(s) - chemistry , alkyl , aryl , alkylation , medicinal chemistry , acetanilide , hydrolysis , organic chemistry , catalysis
Syntheses of Some Alkyl‐, Cycloalkyl‐ and Aryl‐(4‐aminophenyl)‐sulfones Syntheses of (4‐aminophenyl)‐alkyl, ‐cycloalkyl and ‐aryl sulfones 2 were achieved both by alkylation of 4‐(acetylamino)‐benzenesulfinic acid ( 7 ) to the corresponding acetanilides 9 followed by hydrolysis and by oxidation of the appropriate (4‐nitrophenyl)‐sulfides 11 to (4‐nitrophenyl)‐sulfones 1 with subsequent Béchamp reduction.
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