Premium
Saponins with Molluscicidal Properties from Lonicera nigra L
Author(s) -
Domon Bruno,
Hostettmann Kurt
Publication year - 1983
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19830660204
Subject(s) - chemistry , biomphalaria glabrata , caprifoliaceae , triterpenoid , column chromatography , bark (sound) , silica gel , glycoside , snail , molluscicide , two dimensional nuclear magnetic resonance spectroscopy , chromatography , stereochemistry , schistosomiasis , botany , zoology , ecology , physics , schistosoma mansoni , acoustics , helminths , biology
Eight triterpenoid saponins (1–8) have been isolated from the berries of Lonicera nigra L . (Caprifoliaceae) by combination of droplet counter‐current chromatography and column chromatography on silica. The structures have been established by 1 H‐NMR., 13 C‐NMR. spectroscopy, FD.‐MS., FAB.‐MS. and D./CI.‐MS., and on the basis of acidic and basic hydrolyses. The monodesmosidic saponins 1–5 possess strong molluscicidal activity against the schistosomiasis‐transmitting snail Biomphalaria glabrata , whereas the bidesmosidic saponins 6–8 are inactive.