Nucleoside und Nucleotide. Teil 20. Synthese von Desoxyribooligonucleotiden nach der Diester‐ und Triestermethode mit 2(1 H )‐Pyrimidinon als Base

Nucleosides and Nucleotides. Part 20, Synthesis of Desoxyribooligonucleotides According to the Diester and Triester Method with 2(1 H )‐Pyrimidinone as Base The syntheses of the dinucleosidemonophosphate 1‐(2′‐deoxy‐b̃‐ D ‐ribofuranosyl)‐2(1 H )‐pyrimidinon‐(3′‐5′)‐2′‐deoxycytidine (M d pC d ; 4 ) and the trinucleoside‐diphosphate thymidyl‐(3′‐5′)‐thymidylyl‐(3′‐5′)‐1‐(2′‐deoxy‐b̃‐ D ‐ribofuranosyl)‐2(1 H )pyrimidinon (T d pT d pM d ; 1 ) are described, Compound 1 was synthesized by different variants of the triester method, and 4 by the diester method as well as the triester method.