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132. The Synthesis of Highly Strained Monocyclic and Bicyclic β‐Lactams (Δ 1 ‐Carbapenem)
Author(s) -
Hakimelahi Gholam Hosein
Publication year - 1982
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19820650508
Subject(s) - chemistry , bicyclic molecule , lactam , carbapenem , stereochemistry , beta lactam , combinatorial chemistry , biochemistry , antibiotics
The synthesis of some β‐lactams and one Δ 1 ‐carbapenem is described. The electronic activation of monocyclic β‐lactams of type 1 is not sufficient to generate a bioactive compound.