Synthetic Methods and Reactions. Part 106. Suppression of anchimerically assisted rearrangement products in the synthesis of α‐fluorocarboxylic acids from α‐amino acids with 48:52 (w/w) hydrogen fluoride/pyridine [1] | Zendy

Olah George A. | Zendy; Surya Prakash G. K. | Zendy; Chao Yah Li | Zendy

Premium

Synthetic Methods and Reactions. Part 106. Suppression of anchimerically assisted rearrangement products in the synthesis of α‐fluorocarboxylic acids from α‐amino acids with 48:52 (w/w) hydrogen fluoride/pyridine [1]

Author(s) -

Olah George A.,

Surya Prakash G. K.,

Chao Yah Li

Publication year - 1981

Publication title -

helvetica chimica acta

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.74

H-Index - 82

eISSN - 1522-2675

pISSN - 0018-019X

DOI - 10.1002/hlca.19810640806

Subject(s) - chemistry , hydrogen fluoride , pyridine , reagent , fluoride , hydrogen , medicinal chemistry , amino acid , organic chemistry , inorganic chemistry , biochemistry

Anchimerically assisted rearrangement, observed in the fluorination of some α‐amino acids with 70 : 30 (w/w) hydrogen fluoride/pyridine (by weight) in the presence of NaNO 2 , is substantially or fully suppressed by using the less acidic reagent 48 : 52 (w/w) hydrogen fluoride/pyridine.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research