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Improved Nitroaldol Reactions and Reductive Routes to Vicinal Aminoalcohols
Author(s) -
Colvin Ernest W.,
Beck Albert K.,
Seebach Dieter
Publication year - 1981
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19810640732
Subject(s) - vicinal , chemistry , regioselectivity , reduction (mathematics) , combinatorial chemistry , organic chemistry , catalysis , geometry , mathematics
Regioselective and flexible procedures are described for the preparation of a variety of protected vicinal nitroalcohols 1 , 3 and 5 (see Scheme 5 ), as is an efficient method for their reduction to the corresponding vicinal aminoalcohols 2 , 4 and 6 .
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