Premium
NMR.‐spektroskopische Methoden als Reinheitskriterien isomerer Weinsäuren und Weinsäureester
Author(s) -
Pfenninger Armin,
Hochrainer August
Publication year - 1981
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19810640533
Subject(s) - chemistry , tartaric acid , diastereomer , enantiomer , reagent , nuclear magnetic resonance spectroscopy , chloride , chiral resolution , organic chemistry , medicinal chemistry , stereochemistry , citric acid
NMR.‐spectroscopic Methods as Criteria of the Purity of Isomeric Tartaric Acids and Their Esters meso ‐Tartaric acid ( 2 ) can be distinguished either from the natural (+)‐(2 R , 3 R )‐tartaric acid ( 1 ) or the ‘unnatural’ (−)‐(2 S , 3 S )‐tartaric acid ( 1 ′) or their racemic mixture, by 1 H‐NMR.‐spectral resolution using europium chloride in aqueous solution. Diastereomeric esters have been prepared from different esters of tartaric acid 3 and the Mosher reagent 4 and the purities of the enantiomers of 3 have been checked by 1 H‐NMR. spectroscopy.