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Novel Approach to the Synthesis of 6‐Substituted 5,6‐Dihydro‐2(2 H )‐pyranones
Author(s) -
Fehr Charles,
Galindo José,
Ohloff Günther
Publication year - 1981
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19810640503
Subject(s) - acrolein , chemistry , lactone , dimer , glutaraldehyde , stereochemistry , organic chemistry , catalysis
Easily accessible dihydropyrans 9, 10, 12 and 19 are precursors for the synthesis of 6‐substituted 5,6‐dihydro‐2 (2 H )‐pyranones and 6‐substituted tetrahydro‐2‐pyranones. Syntheses of massoia lactone ( 3 ), argentilactone ( 5 ), tuberolactone ( 4 ) and jasmine lactone ( 2 ) from acrolein ( 6 ), acrolein dimer ( 7 ) or glutaraldehyde ( 16 ) are described.