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Some Observations Concerning 1 H‐NMR. Spectra of 5‐hydroxy‐ and 5‐acetoxy‐steroid compounds
Author(s) -
Mihailović Mihailo Lj.,
Lorenc Ljubinka,
Pavlović Vladimir,
Fuhrer Hermann
Publication year - 1981
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19810640409
Subject(s) - chemistry , steroid , substituent , proton , nmr spectra database , proton nmr , spectral line , stereochemistry , biochemistry , physics , quantum mechanics , astronomy , hormone
It was found that analysis of the 1 H‐NMR. signals (at 360 (preferably) and/or 100 MHz) of the protons at C (4) and of the equatorial α‐proton at C (6), particularly when these are located in the 2–3 ppm region and therefore convenient for detection and identification, may be of valuable aid in the structural and configurational characterization of 5‐hydroxy‐ and 5‐acetoxy‐steroids (unsubstituted or containing a hydroxy or acyloxy substituent at C (3)).