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Partial Synthesis of 3′‐Hydroxy‐2′‐deoxy‐2″,3″,4″,5″‐tetrahydroverrucarin A. Verrucarins and roridins, 38th Communication [1]
Author(s) -
Notegen EricAndréa,
Tori Motoo,
Tamm Christoph
Publication year - 1981
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19810640132
Subject(s) - chemistry , sesquiterpene , adipic acid , derivative (finance) , terpene , stereochemistry , alcohol , trichothecene , butanone , organic chemistry , biochemistry , financial economics , economics , toxin , solvent
The macrocyclic trichothecene triester 3′‐hydroxy‐2′‐deoxy‐2",3",4",5"‐tetrahydroverrucarin A ( 37 ), has been synthesized starting from the sesquiterpene alcohol verrucarol ( 3 ), adipic acid and a derivative of mevalonic acid ( 14 ). The latter has been prepared from 4‐(tetrahydro‐2‐pyranyloxy)‐2‐butanone ( 9 ).