Premium
Regioselektive Metallierung des Phenylcyclopropans sowie leichte Anlagerung des 1‐Phenylcyclopropyl‐kaliums an Äthylen
Author(s) -
Schlosser Manfred,
Schneider Philippe
Publication year - 1980
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19800630833
Subject(s) - chemistry , metalation , reagent , potassium , ethylene , medicinal chemistry , derivative (finance) , regioselectivity , tetrahydrofuran , sodium , organic chemistry , solvent , catalysis , financial economics , economics
Regioselective Metalation of Phenylcyclopropane and Smooth Addition of 1‐Phenylcyclopropyl Potassium onto Ethylene Whereas pentyl sodium in pentane mainly promotes a hydrogen/metal exchange reaction at the m ‐ and p ‐position of phenylcyclopropane, both the butyllithium/potassium t ‐butoxide reagent and trimethylsilylmethyl potassium in tetrahydrofuran convert phenylcyclopropane exclusively into 1‐phenylcyclopropyl potassium. The latter organometallic derivative adds smoothly onto the double bond of ethylene at temperatures around −40°.