Premium
Dérivés de sucres à groupement gem‐dihalogénoéthényle
Author(s) -
Tronchet Jean M. J.,
Bonenfant AlainP.
Publication year - 1980
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19800630634
Subject(s) - chemistry , reagent , wittig reaction , stereochemistry , group (periodic table) , medicinal chemistry , organic chemistry
Carbohydrate Derivatives Bearing a gem ‐Dihalogenoethenyl Group Treated with the appropriate Wittig reagent, aldehydosugar derivatives ( 1–13 ) led in good to excellent yields to the expected gem ‐difluoro, gem ‐chlorofluoro‐and/or gem ‐dichloroenoses ( 14–29 ). Examples of their dibromo analogues had been previously described (see e.g. [1]) but the diiodo derivatives could not be isolated, The influence of the conditions on the yields is reported as well as spectroscopic properties (particularly the long‐range 13 C, 19 F‐ and 1 H, 19 F‐coupling constants) of these new enoses.