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Synthèse partielle et propriétés oncostatiques des pseudo‐tubulosines, analogues de l'émétine et de la tubulosine
Author(s) -
Seguin Elisabeth,
Koch Michel,
Chenu Evelyne,
Hayat Marcel
Publication year - 1980
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19800630525
Subject(s) - chemistry , emetine , stereochemistry , condensation , pharmacology , medicine , physics , thermodynamics
Partial Synthesis and Oncostatic Properties of Pseudotubulosines, Analogues of Emetine and Tubulosine Pseudotubulosines, structural analogues of emetine and tubulosine, have been synthesized by either Pictet‐Spengler or Bischler‐Napieralski condensation from dihydrocorynantheal or corynantheidal. Spectral data, cytotoxic and oncostatic properties of these new alkaloids are described.