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9, 10‐Secocholesta‐(5 Z )‐5,8(14), 10(19)‐trien‐3β‐ol und 18‐Nor‐14β‐methyl‐9,10‐secocholesta‐(5 E )‐5, 10(19), 13(17)‐trien‐3β‐ol, zwei neue Doppelbindungsisomere des Vitamins D 3 . Strukturelle Abwandlungen am Vitamin D 3 : 5. Mitteilung [1]
Author(s) -
Reischl Wolfgang,
Zbiral Erich
Publication year - 1980
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19800630413
Subject(s) - chemistry , double bond , adduct , stereochemistry , vitamin , vitamin d and neurology , medicinal chemistry , organic chemistry , biochemistry , medicine , endocrinology
9,10‐Secocholesta‐(5 Z )‐5,8(14),10(19)‐triene‐3β‐ol and 18‐Nor‐14β‐methyl‐9,10‐secocholesta‐(5 E )‐5,10(19), 13(17)‐trien‐3β‐ol, two new double bond isomers of vitamin D 3 . Structural modifications of vitamin D 3 : 5. Communication [1] The present paper reports the synthesis and structure elucidation of the two title compounds. Treatment of the 4‐phenyl‐1,2,4‐triazolin‐3,5‐dione adducts of vitamin D 3 with BF 3 O (C 2 H 5 ) 2 and KOH/butanol yields these two new vitamin D 3 double bond isomers.