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Anil‐Synthese. 21. Mitteilung . Über die Herstellung von stilbenyl‐derivaten des pyrazols
Author(s) -
Palmberg Roger B.,
Siegrist Adolf Emil
Publication year - 1979
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19790620613
Subject(s) - chemistry , hypsochromic shift , potassium hydroxide , dimethylformamide , yield (engineering) , substituent , medicinal chemistry , potassium , ring (chemistry) , fluorescence , organic chemistry , physics , materials science , quantum mechanics , solvent , metallurgy
Preparation of Stilbenyl Derivatives of Pyrazoles Schiffs bases derived from 1‐, 3‐ and 5‐( p ‐formylphenyl)phenylpyrazoles and p ‐chloroaniline are reacted with various p ‐tolyl substituted aromatic heterocycles in the presence of dimethylformamide and potassium hydroxide or potassium t ‐butoxide to yield the corresponding heterocyclic substituted stilbenes (anil synthesis). Introduction of a chloro substituent in the 4‐ and 4,5‐positions of the pyrazole system causes a decrease in yield and a hypsochromic shift in the absorption and fluorescence maxima of the title compounds.
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