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Stoffwechselprodukte von Mikroorganismen. 187. Mitteilung . Synthese des 3‐Isobutyl‐4,5‐dimethylisoindolin‐1‐ons, eines Abbauproduktes von Aspochalasin D
Author(s) -
Kupfer Ernst,
KellerSchierlein Walter
Publication year - 1979
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19790620517
Subject(s) - chemistry , regioselectivity , stereochemistry , medicinal chemistry , organic chemistry , catalysis
Metabolites of Microorganisms. Synthesis of 3‐Isobutyl‐4,5‐dimethylisoindolin‐1‐one, a Degradation Product of Aspochalasin D 3‐Isobutyl‐4,5‐dimethylisoindolin‐1‐one ( 1 ) and 3‐isobutyl‐6, 7‐dimethyl‐isoindolin‐1‐one ( 6 ) were synthesized in a non‐regioselective way. The structures could be assigned unequivocally by spectroscopic means. Compound 1 was identical with a degradation product of Aspochalasin D.