Synthese eines 33gliedrigen Polyaminolactams durch Anwendung der «zip»‐Reaktion. 6. Mitteilung über Umamidierungsreaktionen | Zendy

Kramer† Urs | Zendy; Schmid† Hans | Zendy; Guggisberg Armin | Zendy; Hesse Manfred | Zendy

Premium

Synthese eines 33gliedrigen Polyaminolactams durch Anwendung der «zip»‐Reaktion. 6. Mitteilung über Umamidierungsreaktionen

Author(s) -

Kramer† Urs,

Schmid† Hans,

Guggisberg Armin,

Hesse Manfred

Publication year - 1979

Publication title -

helvetica chimica acta

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.74

H-Index - 82

eISSN - 1522-2675

pISSN - 0018-019X

DOI - 10.1002/hlca.19790620317

Subject(s) - chemistry , derivative (finance) , reagent , yield (engineering) , lactam , potassium , medicinal chemistry , stereochemistry , organic chemistry , materials science , financial economics , economics , metallurgy

Synthesis of a 33‐membered Polyaminolactam by Use of the Zip‐reaction The pentaamino lactam derivative 11 was synthesized from the 13‐membered tosylaminolactam 2 . The prolongation of the side chain was achieved using the phthalimido derivative 3 . After removal of the protecting groups the resulting base 11 was treated with KAPA reagent (1,3‐propanediamine/potassium‐3‐aminopropyl‐amid). By zip‐reaction the 33‐membered 13, 17, 21, 25, 29‐pentaaza‐32‐dotriacontanelactam ( 1 ) was formed in 85% yield.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research