Anil‐Synthese. 19. Mitteilung . Über die Herstellung von Stilbenyl‐Derivaten des Isoxazols | Zendy

Berger Hanny | Zendy; Siegrist Adolf Emil | Zendy

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Anil‐Synthese. 19. Mitteilung . Über die Herstellung von Stilbenyl‐Derivaten des Isoxazols

Author(s) -

Berger Hanny,

Siegrist Adolf Emil

Publication year - 1979

Publication title -

helvetica chimica acta

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.74

H-Index - 82

eISSN - 1522-2675

pISSN - 0018-019X

DOI - 10.1002/hlca.19790620315

Subject(s) - chemistry , potassium hydroxide , yield (engineering) , dimethylformamide , medicinal chemistry , potassium , organic chemistry , solvent , materials science , metallurgy

Preparation of Stilbenyl Derivatives of Isoxazoles Schiff 's bases derived from 3‐ and 5‐( p ‐formylphenyl)‐phenylisoxazoles and o ‐ or p ‐chloroaniline are reacted with various p ‐tolyl substituted aromatic heterocycles in the presence of dimethylformamide and potassium hydroxide or potassium t ‐but‐oxide to yield the corresponding heterocyclic substituted stilbenes (‘Anil synthesis’). 5‐[4‐(Chlorphenylimino‐methyl)phenyl]‐phenylisoxazoles react less readily than the corresponding 3‐isomers.

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