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Synthesis of Xanthone‐ O ‐Glycosides. II. . Synthesis of 1‐ O ‐β‐glycosides
Author(s) -
Chari V. Mohan,
Klapfenberger Rosalinde,
Wagner Hildebert,
Hostettmann Kurt
Publication year - 1979
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19790620305
Subject(s) - chemistry , gentianaceae , xanthone , gentiana , glycoside , stereochemistry , botany , biology
Several naturally occurring xanthone‐1‐ O ‐glycosides have been synthesized in order to study monoamine oxidase (MAO) inhibition structure‐activity relationships. The syntheses also confirmed the structures as 1‐β‐ D ‐glucosyloxy‐3‐hydroxy‐5‐methoxyxanthone ( Canscora decussata SCHULT .), 1‐ O ‐β‐primeverosyl‐3, 7, 8‐trimethoxyxanthone (decussatin‐1‐ O ‐primeveroside, Gentiana verna L .) and 1‐ O ‐β‐primeverosyl‐3, 8‐dimethoxy‐7‐hydroxyxanthone (gentiacaulein‐1‐ O ‐β‐primeveroside, Gentiana verna L .).