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Eine einfache Veresterungsmethode im Eintopf‐Verfahren
Author(s) -
Stadler Paul Albert
Publication year - 1978
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19780610515
Subject(s) - chemistry , dimethylformamide , phenols , phenol , reagent , pyridine , alcohol , yield (engineering) , organic chemistry , solvent , primary (astronomy) , derivative (finance) , materials science , physics , astronomy , economics , financial economics , metallurgy
A simple one‐pot method for esterification A one‐pot procedure for esterifications of primary, secondary and tertiary alcohols and of phenols in high yield is described. Reaction of oxalylchloride with dimethylformamide in a suitable solvent affords dimethylformamide imidechloride; addition of an acid to the suspension of this reagent furnishes an activated carboxy‐group derivative, which is then transformed to an ester by addition of pyridine and an alcohol ro a phenol. Reaction temperatures needed for esterification are low, usually 0° to room temperature, reaction times are short.