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Zur Biogenese des Muscarins in Mycelkulturen von Clitocybe rivulosa
Author(s) -
Nitta Keiichi,
Stadelmann René Josef,
Eugster Conrad Hans
Publication year - 1977
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19770600529
Subject(s) - chemistry , muscarine , stereochemistry , biosynthesis , derivative (finance) , organic chemistry , biochemistry , receptor , muscarinic acetylcholine receptor , financial economics , economics , enzyme
Studies on the biosynthesis of muscarine in mycelial cultures of Clitocybe rivulosa The incorporation and distribution of several 14 C‐labelled simple compounds into muscarine has been investigated with mycelial cultures of Clitocybe rivulosa . Specifically, the carbon atoms 1, 2 and 3 of pyruvate are incorporated into C H 3 ‐C(2), C(2) and C(3), and the carbon atoms 2, 3 and 4 of glutamate into C(4), C(5) and CH 2 ‐C(5) of muscarine. The carbon atoms 1 and 5 of glutamate are lost during the biosynthesis. Therefore, muscarine can be regarded as a derivative of glutamate.