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Reaktionen mit γ‐Chloracetessigesterderivaten
Author(s) -
Boosen KarlJosef
Publication year - 1977
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19770600415
Subject(s) - chemistry , aniline , ethyl acetoacetate , ammonia , ethyl ester , organic chemistry , medicinal chemistry , catalysis
Reactions with derivatives of γ‐chloroacetoacetic acid Ethyl γ‐chloroacetoacetate reacts with ammonia to give ethyl β‐amino‐γ‐chloro‐crotonate; with aniline, however, β‐anilino‐crotonic acid γ‐lactone is formed. The reaction of ethyl α‐cyano‐γ‐chloro‐acetoacetate with arylamines yields 1‐aryl‐2‐amino‐3‐ethoxycarbonyl‐pyrrolin‐4‐ones.