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An Efficient Approach to Patchouli Alcohol Analogues
Author(s) -
Näf Ferdinand,
Decorzant René,
Thommen Walter
Publication year - 1977
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19770600407
Subject(s) - patchouli , chemistry , undecane , decane , alcohol , derivative (finance) , ring (chemistry) , organic chemistry , stereochemistry , medicinal chemistry , chromatography , essential oil , financial economics , economics
A short approach to the tricyclo [5.3.1.0 3,8 ] undecane derivatives 1, 10, 11 and 12 and to the tricyclo [4.3.1.0 3,7 ] decane derivative 2 , starting from industrially available intermediates, is described. Of the compounds 1 , 10 , 11 , and 12 , which possess the ring system of patchouli alcohol, 12 also exhibits a woody, patchouli‐like note. The 1 H‐NMR.‐spectra of 1 , 2 and 8 – 12 are discussed.
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